May 26, 2023 13:09
12 mos ago
25 viewers *
Spanish term

VISD

Spanish to English Medical Medical (general)
Labs (under units)

Nombre: Aldosterona Unidades: VISD Valores de Normalidad: Hasta 160 Muestra: suero

I am stumped on "VISD". Thank you for your help with this one!
Proposed translations (English)
2 VISD

Discussion

Chema Nieto Castañón May 28, 2023:
Not really helpful, Ecuánime.
Is there any other entry for aldosterone or is this the only one?
Are there any other non-common units under "Unidades"? If so, what does it say in Unidades and Nombre?
Ecuánime (asker) May 27, 2023:
As for context, there's not much else in terms of Aldosterone, as it is part of a 12-page lab report, with hundreds of other items and reference ranges. For clarification, the headings of the lab tables are: Nombre, Unidades, Valores de Normalidad, Muestra. "VISD" is only listed under "Unidades" for Aldosterone, and nowhere else. Tell me if this helps and thanks for the suggestions thus far.
Chema Nieto Castañón May 26, 2023:
¿Unidades SI? Como señala phil, ese 160 de valor máximo encajaría con el valor máximo de referencia de aldosterona plasmática en adultos acostados (versus la muestra tomada en adultos sedentes o en pie, cuyos valores son más altos), expresada en picogramos por mililitro (pg/mL). Ver aquí por ejemplo (el valor de 3-16 nanogramos por decilitro (ng/dL) es equivalente al 30-160 pg/mL):
https://espanol.kaiserpermanente.org/es/health-wellness/heal...

Con todo, me planteaba que ese críptico VISD podría ser una especie de typo por unidades SI (sistema internacional), que expresarían el valor de la aldosterona plasmática en nmol/L (o pmol/L). Sin embargo ese valor de 160 como máximo (que podría corresponder a pmol/L) resulta demasiado bajo en cualquier supuesto (160 pmol/L serían equivalentes a 0.16 nmol/L; ver en el enlace de más arriba rangos de referencia).

Así, tal vez algo más de contexto para entender qué valor de aldosterona se está midiendo y cómo leer ese "160" podría ayudar a dilucidar qué se quiere decir con VISD.
philgoddard May 26, 2023:
The normal reference ranges of angiotensin II, renin, and aldosterone were 25–60 pg/mL, 0.15–2.33 ng/mL/hr., and 30–160 pg/mL, respectively.
http://bmccardiovascdisord.biomedcentral.com/articles/10.118...
pg is picogram, a trillionth of a gram.
Marie Wilson May 26, 2023:
Difficult one, I can't find anything even remotely useful!
Helena Chavarria May 26, 2023:
@Phil Yes, you're quite right. It hadn't occurred to me.
philgoddard May 26, 2023:
Maybe But that's not a unit.
Helena Chavarria May 26, 2023:
If it's:

Nombre: Aldosterona
Unidades: VISD
Valores de Normalidad: Hasta 160
Muestra: suero

then 'VISD' could stand for 'viscosidad dinámica' (dynamic viscosity)

Proposed translations

1 day 1 hr
Selected

VISD

After some research, VISD seems to be a silicone planar photodiode used in the detection of molecules. HPLC-PDA (photodiode array) is typically used for molecule detection, it seems like here they're just using the name of the photodiode here for some reason.

First I found it here:
https://www.labor-gaertner.de/fileadmin/user_upload/Dokument...
Page 3, Test technique HPLC/UV/VISD.

Then I started looking for a test technique and found there's a product called VISD made by World Precision Instruments and it's a model of silicon photodiode detector:

https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&d...

https://www.jstage.jst.go.jp/article/analsci/14/4/14_4_809/_...

http://nathan.instras.com/documentDB/paper-195.pdf

If you google "wpi visd detector", a bunch of articles that use it to detect different molecules pop up.

And then here's an article showing that aldosterone can be detected using a photodiode:
https://patents.google.com/patent/US20200124622A1/en

It's the only thing that makes sense to me. But it is a guess, because I'm not sure why they would put it in the units column (unless there's not a better place) or whether there are techniques listed for other parameters. Good luck!
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4 KudoZ points awarded for this answer. Comment: "Thank you for your help on this one!"

Reference comments

10 hrs
Reference:

median plasma aldosterone concentration (PAC) normal range: 30–160 pg / mL

Plasma aldosterone levels are associated with increased cardiovascular mortality: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
https://academic.oup.com › article
Andreas Tomaschitz · 2010 · — Median plasma aldosterone concentration (PAC) was 79.0 (48.0–124.0) pg/mL (normal range: 30–160) in 3153 patients [median age: 63.5 (56.3–70.6) years; 30.1% women] who had undergone coronary angiography.
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